ABSTRACT
A specific T-cell response persists in the majority of COVID-19 patients 6 months after hospital discharge. This response is more prominent in those who required critical care during the acute COVID-19 episode but is reduced in patients with lung sequelae. https://bit.ly/3fBuVA4.
ABSTRACT
Patients infected by SARS-CoV-2 may develop pneumonia (COVID19) and require hospital admission and, eventually, critical care [1]. This has been related with a weaker innate immune response with impaired production of type I interferons [2]. In this setting, an antigen specific T-cell response is needed for the elimination of SARS-CoV-2, as well as to develop long-lasting memory to respond to potential future SARS-CoV-2 infections [3, 4]. However, this response needs to be contained once the virus is eradicated to avoid further damaging the host.